Fig. 3: Mapping of the μs-ms dynamics of the eIF4G-interacting domains.

a Left: Residue-specific R_ex values of the J domain. The residues that could not be analyzed quantitatively, due to extensive conformational exchanges in the μs-ms time scale, are shown as gray backgrounds. Middle and right: Mapping of the R_ex values in the secondary structure (middle) and tertiary structure of the previously reported J domain (right, PDB ID: 2NBY)⁹. The Ade/Gua residues that exhibited R_ex values larger than 10 s⁻¹ are colored red, whereas those between 5 and 10 s⁻¹ are cyan. Source data are provided as a Source Data file. b Left: Residue-specific R_ex values of the StA_SL domain. Residues that could not be analyzed quantitatively, due to extensive conformational exchanges in the μs-ms time scale, are shown with a gray background. Middle and right: Mapping of the R_ex values in the secondary structure (middle) and tertiary structure model (right), which is derived from the previously reported structure of the ΔJΔK domain⁹ (PDB ID: 2NC1) by substituting the GAAA tetraloops with the UUCG tetraloops. The Ade/Gua residues that exhibited R_ex values larger than 10 s⁻¹ are colored red, whereas those between 5 and 10 s⁻¹ are cyan. Source data are provided as a Source Data file. Error bars indicate experimental errors derived from the signal-to-noise ratio of each correlation, as written in Methods.