Table 1 BTSC lines used for drug screening representing genetic variability

From: Epigenetic and molecular coordination between HDAC2 and SMAD3-SKI regulates essential brain tumour stem cell characteristics

BTSC ID

Age

Sex

Diagnosis

MGMT status

EGFR status

p53 status

PTEN status

IDH1/2 status

BT48

68

Male

GBM

M

mt

wt

het

wt/wt

BT50

61

Male

GBM

um

wt

wt

het

wt/wt

BT67

44

Male

GBM

M

wt

wt

het

wt/wt

BT69

50

Male

GBM/GS

um

het

wt

mt

wt/wt

BT89

59

Female

GBM

M

wt

wt

wt

wt/wt

BT94

60

Female

GBM

M

wt

wt

mt

wt/wt

BT147

56

Male

GBM-r

U

vIII

mt

mt

Wt/wt

BT189

55

Female

GBM

U

wt

mt

wt

wt/wt

BT248Z

56

Female

GBM

M

wt

mt

wt

wt/wt

  1. GBM-r recurrent GBM, um hemimethylated, U unmethylated, M methylated, mt mutated, wt wildtype, het heterozygous.