Table 1 Antibacterial activity of CEF in the absence and presence of different metal compounds against different bacteria
From: Metallo-sideromycin as a dual functional complex for combating antimicrobial resistance
MIC of CEF (μM) | ||||||||
|---|---|---|---|---|---|---|---|---|
In the presence of 50 μM of metal compounds | ||||||||
Strains | Alone | Bi3+ | Ga3+ | Co3+ | Cr3+ | Fe3+ | Mn2+ | Ti4+ |
P. aeruginosa PAO1 | 4 | 0.06 | 0.06 | 4 | 4 | 4 | 8 | 4 |
P. aeruginosa PA14 | 4 | 0.12 | 0.06 | 4 | 4 | 8 | 8 | 4 |
P. aeruginosa ATCC27853 | 2 | 0.12 | 0.12 | 4 | 4 | 4 | 4 | 4 |
B. cepacia ATCC25416 | 2 | 0.03 | 0.06 | 4 | 2 | 2 | 4 | 2 |
B. cepacia J2315 | 0.5 | 0.03 | 0.03 | 4 | 0.5 | 0.5 | 0.5 | 0.5 |
E. coli ATCC25922 | 1 | 1 | 1 | 1 | 1 | 2 | 2 | 1 |
E. coli ATCC10536 | 0.03 | 0.03 | 0.03 | 0.125 | 0.03 | 0.06 | 0.06 | 0.03 |
E. coli (NDM-1)+ | 1 | 1 | 1 | 2 | 1 | 2 | 4 | 2 |
E. coli clinical | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |