Table 2 Prioritized six eQTL SNPs for PCCB
Source | References | Best GWAS SNP | LD eSNP | LD (r2) | Ref/Alt | Chromatin states (Core 15-state model) | PsychENCODE ATAC-seq Peak |
|---|---|---|---|---|---|---|---|
MR-JTI | Wu et al., Mol. Neurobiol.14 | – | – | – | – | – | – |
TWAS | Hall et al., Hum. Mol. Genet.9 | rs7432375 | rs6791142 | 0.81 | T/C | 7_Enh | YES |
rs35874192 | 0.62 | G/C | 1_TssA | YES | |||
rs900818 | 0.63 | C/T | 1_TssA, 2_TssAFlnk | YES | |||
Huckins et al., Nat. Genet.11 | – | – | – | – | – | – | |
Gusev et al., Nat. Genet.8 | rs7432375 | rs7616204 | 0.64 | C/T | 7_Enh | YES | |
Gandal et al., Science10 | rs7427564 | rs6791142 | 0.73 | T/C | 7_Enh | YES | |
SMR | Gandal et al., Science10 | rs527888 | rs570621 | 0.95 | A/G | 7_Enh | YES |
rs7349597 | 0.69 | C/T | 1_TssA, 2_TssAFlnk, 7_Enh | YES | |||
Li et al., Nat. Genet.12 | rs66691851 | rs7349597 | 0.6 | C/T | 1_TssA, 2_TssAFlnk, 7_Enh | YES | |
rs570621 | 0.81 | A/G | 7_Enh | YES | |||
rs6791142 | 0.6 | T/C | 7_Enh | YES |
