Fig. 7: In vivo antitumor performance of the self-triggered thermoelectric system.
From: Self-triggered thermoelectric nanoheterojunction for cancer catalytic and immunotherapy
a Experimental illustration of in vivo antitumor therapy. b, c Antitumor performance of different treatments, including control, BST, CaO2 and BST/CaO2, on a subcutaneous xenograft colorectal cancer animal model. Data are presented as the mean ± s.d. (n = 5 biologically independent mice). Statistical differences were analyzed by Student’s two-sided t-test. d, e Antitumor performance of different treatments, including control, BST, CaO2 and BST/CaO2, on an orthotopic colorectal cancer animal model. Data are presented as the mean ± s.d. (n = 5 biologically independent mice). Statistical differences were analyzed by Student’s two-sided t-test. f The survival curves of tumor-bearing mice under different treatments. g, h Flow cytometry analysis of the percentage of DC maturation and migration to lymph nodes (CD11c+ CD80+ CD86+) under different treatments. Data are presented as the mean ± s.d. (n = 3 biologically independent mice). Statistical differences were analyzed by Student’s two-sided t-test.
