Table 1 Hazard ratios for select diagnoses

From: Diurnal rhythms of wrist temperature are associated with future disease risk in the UK Biobank

PheCODE

HR at 2 SD

HR at 1 °C

N

NAFLD (Other chronic nonalcoholic liver disease)

1.91 (1.58–2.31)

1.43 (1.28–1.58)

603

Type 2 diabetes

1.69 (1.53–1.88)

1.34 (1.26–1.42)

1936

Extrapyramidal disease and abnormal movement disorders

1.67 (1.32–2.11)

1.33 (1.16–1.51)

293

Sleep disorders

1.50 (1.3–1.74)

1.25 (1.15–1.36)

864

Renal failure

1.25 (1.14–1.37)

1.13 (1.07–1.19)

2310

Essential hypertension

1.23 (1.17–1.3)

1.12 (1.09–1.16)

6143

Diverticulosis

1.20 (1.13–1.28)

1.11 (1.07–1.14)

4528

Pneumonia

1.22 (1.11–1.33)

1.11 (1.06–1.17)

2256

Disorders of lipida metabolism

1.16 (1.09–1.24)

1.09 (1.05–1.13)

4072

Osteoarthrosis

1.12 (1.04–1.21)

1.06 (1.02–1.11)

2921

Anxiety disorders

1.11 (0.99–1.24)

1.06 (1.0–1.12)

1555

Parkinson’s disease

0.76 (0.59–0.97)

0.86 (0.75–0.98)

295

  1. From the Cox proportional hazards models, wrist temperature amplitudes associated with disease outcomes. Twelve of the largest significant effect sizes are shown, as hazard ratios comparing mean to two standard deviations (SD) below, corresponding to 1.8 °C, below mean amplitude, or comparing to 1 °C below the mean, along with the number of events (cases). See also Supplementary Data 1 for full results.
  2. aPheCODE Map25, 26 uses the term “lipoid”.
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