Fig. 4: F16BP MPs rescue DCs in adoptive cellular transfer (ACT) therapy model, in vivo. | Nature Communications

Fig. 4: F16BP MPs rescue DCs in adoptive cellular transfer (ACT) therapy model, in vivo.

From: Rescue of dendritic cells from glycolysis inhibition improves cancer immunotherapy in mice

Fig. 4: F16BP MPs rescue DCs in adoptive cellular transfer (ACT) therapy model, in vivo.The alternative text for this image may have been generated using AI.

a Schematic representation of the adoptive cellular therapy model employed. b, c Mice injected with adoptively transferred DCs along with F16BP MPs were able to rescue glycolysis and glycolytic capacity from glycolytic inhibition (PFK15), in vivo (n = 6; One-way ANOVA Tukey’s test), d, e Mice injected with adoptively transferred DCs along with F16BP MPs accelerated basal and maximal respiration even under glycolytic inhibition (PFK15), in vivo (n = 6; One-way ANOVA Tukey’s test). Data represented as mean ± std error.

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