Fig. 4: Local magnetic actuation biases growth and proliferation.
From: Targeted mechanical stimulation via magnetic nanoparticles guides in vitro tissue development
a Representative images of day 1 and day 11 hNTmOs under various actuation conditions (n = 3 independent experiments). Schematic representation of day 1 and day 11 hNTmO contours. Growth ratio of hNTmOs for various actuation conditions (n = 3 independent experiments for a total of 17 hNTmOs per condition). Statistical analysis was performed by unpaired two-sided t test. Control-Mag p = 0.0005, No Mag-Mag p = 0.0005. b Representative images for EdU staining of day 11 hNTmOs under various actuation conditions (n = 2 independent experiments). Schematic representation of biased proliferation in hNTmO under the influence of magnetic field. Proliferation ratio of day 11 hNTmOs for various actuation conditions (n = 3 independent experiments for 32 (Control), 30 (No Mag) and 35 (Mag) hNTmOs).Statistical analysis was performed by unpaired two-sided t-test, Control-Mag p = 0.0077, No Mag-Mag p = 0.0176. Scalebars 50 μm. Error bars are SEM. Source data are provided as a Source Data file.
