Fig. 1: Driver events involving NOTCH1 and NRARP in two reninoma cases. | Nature Communications

Fig. 1: Driver events involving NOTCH1 and NRARP in two reninoma cases.

From: Targetable NOTCH1 rearrangements in reninoma

Fig. 1: Driver events involving NOTCH1 and NRARP in two reninoma cases.The alternative text for this image may have been generated using AI.

a Rearrangement plots showing copy number, rearrangements and position on chromosome 9. Boxes detail the position of breakpoints in relation to genes. * highlights exon 28 involved in the inversion in PD54845. b NOTCH1 gene, illustrating where breakpoints occur in each case. c NOTCH1 schematic, illustrating breakpoints occurring in the regulatory region in each case.

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