Fig. 1: The distribution of invasive S. Typhimurium in Africa.

a Maximum likelihood phylogenetic tree of the 1419 S. Typhimurium isolates sequences from this study (summarised in Supplementary Data 1). Sequencing reads were mapped to S. Typhimurium ST313 reference strain D23580. The tree is based on 71521 chromosomal SNPs. Branches are coloured by the country of isolation. Invasive S. Typhimurium clades as identified in this study are annotated. Metadata is visualised on the concentric rings in compliance to the legend, from the inside to outside; (1) Country of origin, (2–5) presence of multidrug resistance markers (MDR; blaTEM, cat, dfrA, sul), (6) invasive S. Typhimurium clades. Branch lengths represent the number of SNPs as indicated in the scale bar. b Distribution of invasive S. Typhimurium clades per country for the studied isolates assigned to an invasive S. Typhimurium clade (1 = ST19-L1, 2 = ST19-L2, 3 = ST19-L3, 4 = ST19-L4, 5 = ST313-L1, 6 = ST313-L2). Bar charts show the number of isolates per clade coloured by the country of isolation. c Distribution of S. Typhimurium isolates over time assigned to an invasive S. Typhimurium clade (1 = ST19-L1, 2 = ST19-L2, 3 = ST19-L3, 4 = ST19-L4, 5 = ST313-L1, 6 = ST313-L2). Historical isolates (older than 1975) were excluded in this representation.