Table 2 Single mutations were chosen from Li et al., 201921

From: Dominance vs epistasis: the biophysical origins and plasticity of genetic interactions within and between alleles

Substitution site (AA)

Substitution site (nt)

Mutation position at the structure

M23L

A67C

surface

L33F

A99C

DNA-binding

K53N

A159C

surface

S55R

C165G

core

V56I

G166A

core

E57K

G169A

surface

E58D

A174T

surface

F59L

T177A

core

  1. The position is indexed based on the Li et al. 21 study. The position in the full protein sequence is +17 aa.