Fig. 3: Catalytic atroposelective synthesis of N-arylindoles.

Unless otherwise noted, the reactions were conducted with 1 (0.050 mmol, 1.0 equiv), 2 (0.075 mmol, 1.5 equiv), P9 (0.005 mmol, 10 mol%, 5.0 mg), and 3 Å molecular sieves (40 mg) in PhMe (0.2 mL) at −5 °C. a20 mol% of P9 was employed. bThe reaction was performed at room temperature with 20 mol% of P9.