Fig. 3: Comparative Hi-C analysis to explore the variability of depletion effects. | Nature Communications

Fig. 3: Comparative Hi-C analysis to explore the variability of depletion effects.

From: Context-dependent perturbations in chromatin folding and the transcriptome by cohesin and related factors

Fig. 3: Comparative Hi-C analysis to explore the variability of depletion effects.

a Normalized Hi-C matrix of a representative chromosomal region (chromosome 21, 26.0–29.0 Mb). b The number of TADs, loops, aggregate peak analysis (APA) strength (observed/expected ratio of the center) and compartment strength (from saddle plots; see also Fig. S3b). The dots indicate the Hi-C samples (including different treatment times). c Relative contact probability for the likelihood of a contact at increasing length scales (averaged across replicates). d Loop length distribution. The color indicates the fraction of loops compared to all loops. Source data are provided as a Source Data file.

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