Fig. 5: Assessment of wound healing.
a Residual bacteria colonies on agar broth plates separated from wounds with different treatments at 12 d. b H&E and Masson staining sections of the wounds with different treatments at 12 d. Inflammatory cells (e.g. neutrophils and lymphocytes) were found in the PG group, while inflammation subsided in the PG-DEG-HEP-COF@Lev, PG-DEG-HEP-COF@Van, and PG-DEG-HEP-COF@Lev&Van groups, along with the presence of a large number of fibroblasts and elongated fibroblasts, which favored the formation of granulation tissue. Masson staining demonstrated collagen formation and distribution during wound healing. At 12 d, the wounds treated with PG-DEG-HEP-COF@Lev&Van membrane exhibits more collagen fibers (dark blue) than other groups, which are uniformly distributed and extended to the epidermis, indicating that the capability to facilitate wound healing of PG-DEG-HEP-COF@Lev&Van membrane is better than those of other test membranes. c Routine blood indicators at 4 d and 12 d (WBC, white blood cells; RBC, red blood cells; HGB, hemoglobin; HCT, red blood cell pressure product; PLT, platelets). For each group, nâ=â3 independent samples. At 4 and 12 d, the number of WBC in the PG-treated group exceeded the normal range, while all routine blood indicators were within the normal range for other membrane-treated groups. The shaded pink squares in Fig. 5c represent the normal range of routine blood indicators. For a, b, three independent samples were recorded, and one representative image is shown. The data in c are presented as meanâÂħâSD. Source data are provided as a Source Data file.
