Fig. 8: HPRT1 expression predicts poor prognosis of GBM patients. | Nature Communications

Fig. 8: HPRT1 expression predicts poor prognosis of GBM patients.

From: Hypoxanthine phosphoribosyl transferase 1 metabolizes temozolomide to activate AMPK for driving chemoresistance of glioblastomas

Fig. 8: HPRT1 expression predicts poor prognosis of GBM patients.

a and b Kaplan–Meier survival analysis based on HPRT1 expression from collected primary GBM samples (a) and the indicated GBM datasets (b). c Kaplan–Meier survival analysis based on HPRT1 expression from the indicated glioma datasets. d–f Kaplan–Meier survival analysis based on HPRT1 (d), AMPK pT172 (e), and RRM1 pT52 (f) expression from collected recurrent GBM samples. g–i The Pearson correlation test was used to analyze the correlation among HPRT1, AMPK pT172, and RRM1 pT52. Statistics: a–f Log-rank test for two-group comparison. Source data are provided as a Source Data file.

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