Fig. 7: Upregulation of human Enolase 1 gene in hippocampus in women during aging.
From: Estrogen receptor beta in astrocytes modulates cognitive function in mid-age female mice
a Analysis of human hippocampus microarray data of in women (GSE11882, ages: 26–99 years old, n = 21). Higher gene expression levels of Enolase 1 (ENO1) correlated with older ages (r = 0.526; p = 0.014, blue line). b Human ENO1 gene expression was increased in females at menopausal ages (>60 years, n = 13) compared to younger ages (<50 years, n = 8), two-sided Mann–Whitney U test. For the box-and-whisker plots, the box indicates the median and 25–75th percentile range, and the whiskers extend to a maximum of 1.5 times the interquartile range beyond the box.
