Fig. 7: MS neurons show phase coupling to hippocampal tSCs in anesthetized rats.

a Mean amplitude of supra-theta spectral components as a function of theta phase was computed from the raw LFP of an example session of an anesthetized rat, for all cycles (top left) and for cycles strongly expressing a given tSC. Two theta cycles are shown, indicated by the white cosine curves. b Average tSCs spectra in anesthetized rats (n = 6). Error shades show the standard error of the mean. Median peak frequencies for all recordings are shown in the brackets. c Proportion of theta cycles expressing each tSC (n = 13 sessions). Boxes and whiskers show median, interquartile range and non-outlier range. Insets show the proportion of theta cycle expressing any of the tSCs. d Left, Z-scored phase histograms of all tSC-coupled MS neurons, sorted into four groups based on the tSC they are coupled to (blue, low firing rate; yellow, high firing rate). Zero phase corresponds to tSC troughs (white vertical lines). Cells within each group are sorted by their preferred phase in two blocks: top, cells with maximum firing rate before the most negative tSC trough; bottom, cells with maximal firing after the most negative tSC trough. Right, number of neurons phase-coupled to a given tSC. Source data are provided as a Source Data file.