Fig. 2: Centrosome amplification profiles across 318 tissue samples. | Nature Communications

Fig. 2: Centrosome amplification profiles across 318 tissue samples.

From: Molecular landscape and functional characterization of centrosome amplification in ovarian cancer

Fig. 2: Centrosome amplification profiles across 318 tissue samples.The alternative text for this image may have been generated using AI.

Centrosome amplification scores across 287 HGSOC tissue samples, 24 fallopian tube, 1 spleen, 1 kidney, and 5 liver samples. Each boxplot represents CA scores across up to 50 imaging fields from individual tissue samples. Different tissue types are indicated by different colours. Dashed vertical line indicates the CA cutoff threshold of ~1.83. Samples with median CA scores > CA cutoff were considered to have significant CA. Boxplots show 25th, 50th and 75th centiles; whiskers indicate 75th centile plus 1.5 × inter-quartile range and 25th centile less 1.5 × inter-quartile range. Notches on boxes extend 1.58 × inter-quartile range/sqrt(n) approximating to the 95% confidence interval for comparing medians. Source data are provided as a Source Data file.

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