Fig. 5: Integration of embryonic development between xenopus and zebrafish. | Nature Communications

Fig. 5: Integration of embryonic development between xenopus and zebrafish.

From: Benchmarking strategies for cross-species integration of single-cell RNA sequencing data

Fig. 5

a UMAP visualisation of unintegrated data of xenopus and zebrafish embryonic development. Cells are coloured by their cell types and the developmental stages as in HPF. b UMAP visualisation of integration results of five top-performing algorithms and SAMap, organised by decreasing integrated score and coloured by species or cell type. Note that 5 types of Neural_crest cells in zebrafish were combined into Neural_crest in the integration for matching with xenopus. All strategies were ranked by integrated score and for the top 5 integration algorithms, the homology strategy with the highest integrated score was shown. The respective species mixing and biology conservation scores were also shown. The scores were not calculated for SAMap (not applicable, see Methods for details). SM, species mixing score; BC, biology conservation score; HPF, hour post fertilisation.

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