Fig. 5: The design of Dox-inducible promoters in HEK293 cells.
From: Deep flanking sequence engineering for efficient promoter design using DeepSEED
a The design process of the Dox-inducible promoters. b Schematic representation of the template, DeepSEED-designed, and combination promoter construction tested in vivo. c, d Two-dimensional images showing the induced promoter activity and fold-change of the designed promoters, 3-tetO DeepSEED designed promoters in c, and 7-tetO combination promoters in d. Numbers 1 to 5 in c represent selected 3-tetO promoters and they were combined to generate the 7-tetO promoters in d. Each dot represents the average of three biological replicates. Source data are provided as a Source Data file.
