Fig. 1: Alternation of gut microbiota in HTGP patients. | Nature Communications

Fig. 1: Alternation of gut microbiota in HTGP patients.

From: Gut microbiota aggravates neutrophil extracellular traps-induced pancreatic injury in hypertriglyceridemic pancreatitis

Fig. 1

a Schematic representation of human study design (healthy volunteers, n = 16; high triglycerides matched controls, n = 8; HTGP patients, n = 25). b Alpha diversity (based on simpson, P = 0.0421). c Nonmetric multidimensional scaling (NMDS) plot clustering differential microbial distributions between groups. d Relative abundance of gut bacteria in the genus level. Top 20 average abundance of microbes were compared. e The hierarchical clustering heatmap of differential bacterial species (Bacteroides uniformis, HC vs HTGP, P = 0.0001). f LEfSe indicating differential bacterial taxa between HC and HTGP groups. LDA score of differentially abundant bacterial taxa (LDA > 4, p: Phylum, c: Class, o- Order, f: Family, g: Genus, s: Species). g Correlation analysis between different genera and clinical outcomes in HTGP patients, as well as indicators of disease severity. P values were determined by two-tailed ordinary one-way ANOVA with the Tukey post hoc test or Student’s t-test. Data was represented as mean ± SEM. *p < 0.05, **p < 0.01, ***p < 0.001. Source data are provided as a Source data file.

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