Fig. 5: Validation of the association of cardiometabolic risk factors with metabolic discordant groups. | Nature Communications

Fig. 5: Validation of the association of cardiometabolic risk factors with metabolic discordant groups.

From: Metabolic phenotyping of BMI to characterize cardiometabolic risk: evidence from large population-based cohorts

Fig. 5: Validation of the association of cardiometabolic risk factors with metabolic discordant groups.

Linear regression analyses between metabolic traits (outcomes) and the discordant mBMIΔ groups (predictor, Q5 relative to Q1) were performed adjusting for (a) age, sex, and BMI and (b) age, sex, BMI, total cholesterol, HDL-C, and triglycerides (excluding the outcome) in the AusDiab cohort, n = 10, 339 (blue green boxes) and the BHS cohort, n = 4492 (pink boxes). Each square represents the fold difference (Q5 relative to Q1 of mBMIΔ) for a given metabolic trait. The whiskers represent 95% CIs. HDL-C high density cholesterol, HOMA-IR homeostatic model assessment of insulin resistance, FBG fasting blood glucose, SBP systolic blood pressure, DBP diastolic blood pressure.

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