Fig. 6: The relationship between mBMIΔ and T2DM. | Nature Communications

Fig. 6: The relationship between mBMIΔ and T2DM.

From: Metabolic phenotyping of BMI to characterize cardiometabolic risk: evidence from large population-based cohorts

Fig. 6: The relationship between mBMIΔ and T2DM.

a Density histogram showing the distribution of BMI in T2DM and NGT subjects. b Density histogram showing the distribution of mBMI in T2DM and NGT subjects. c The forest plot displays the odds ratio (x-axis) associated with moving from Q1 of mBMIΔ (reference quintile) to Q2–Q5 (y-axis) for the newly diagnosed prevalent T2DM (yellow circles) and 5-year incident T2DM (sky-blue circles) compared to controls. The odds ratios were computed from a multiple logistic regression between a newly diagnosed prevalent T2DM, n = 395 versus 7733 NGT subjects at baseline or incident T2DM, n = 218 cases versus 5354 controls free of T2DM and the quintiles of the mBMIΔ (Q1 as a reference) adjusted for age, sex, and BMI. Error bars represent 95% CIs. Odds ratios and the associated CIs were log2 transformed to enhance visualization. The results for clinical lipid, familial history of diabetes and smoking status adjusted models are provided in Supplementary Table 5.

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