Fig. 2: Change in weight and percent body fat during the 12-week intervention.

Results are presented as boxplots for all participants (a, d), as well as for fat-responders (b, e) and carbohydrate responders (c, f) separately. a Genotype-concordant group (n = 60, genotype-discordant group (n = 62); b high-fat diet (n = 44), high-carbohydrate diet (n = 41); c high-carbohydrate diet (n = 16), high-fat diet (n = 21); d genotype-concordant group (n = 58), genotype-discordant group (n = 60); e high-fat diet (n = 42), high-carbohydrate diet (n = 40); f high-carbohydrate diet (n = 16), high-fat diet (n = 20). In the boxplots, the center line denotes the median value (50th percentile), the bounds of the box represent the 25th and 75th percentiles of the dataset, and the whiskers mark the 5th and 95th percentiles.