Table 5 Change in items of the Diet Personalization Survey during the 12-week intervention in those assigned to a diet concordant vs. discordant with the genotype

From: The Personalized Nutrition Study (POINTS): evaluation of a genetically informed weight loss approach, a Randomized Clinical Trial

All participants

Genotype-concordant diet (n = 60)

Genotype-discordant diet (n = 62)

 

Meana (SD)

Meana (SD)

Adj. differenceb (95% CI)

The assigned diet…

… fits my typical eating habits

0.9 (0.5)

1.3 (0.6)

−0.3 (−1.2, 0.6)

… fits my lifestyle

0.4 (0.6)

0.2 (0.6)

0.2 (−0.7, 1.1)

… makes it easier to lose weight

0.6 (0.5)

0.7 (0.6)

0.1 (−0.8, 0.8)

I am confident that I can…

… successfully lose weight on the assigned diet

0.4 (0.5)

0.6 (0.5)

−0.1 (−0.8, 0.7)

… follow the assigned diet

−0.7 (0.4)

−0.4 (0.5)

−0.3 (−0.9, 0.4)

Fat-responders

High-fat diet (n = 44)

High-carbohydrate diet (n = 41)

 

Meana (SD)

Meana (SD)

Adj. differenceb (95% CI)

The assigned diet…

… fits my typical eating habits

0.6 (0.6)

1.3 (0.7)

−0.6 (−1.6, 0.4)

… fits my lifestyle

0.0 (0.7)

0.2 (0.8)

−0.1 (−1.2, 1.0)

… makes it easier to lose weight

0.2 (0.7)

0.4 (0.7)

−0.1 (−1.1, 0.9)

I am confident that I can…

… successfully lose weight on the assigned diet

0.1 (0.6)

0.4 (0.7)

−0.1 (−1.1, 0.8)

… follow the assigned diet

−0.9 (0.6)

−0.5 (0.6)

−0.4 (−1.2, 0.5)

Carbohydrate-responders

High-carbohydrate diet (n = 16)

High-fat diet (n = 21)

 

Meana (SD)

Meana (SD)

Adj. differenceb (95% CI)

The assigned diet…

… fits my typical eating habits

1.6 (1.1)

1.3 (1.2)

0.4 (−1.4, 2.2)

… fits my lifestyle

1.1 (1.0)

0.3 (1.1)

1.0 (−0.7, 2.7)

… makes it easier to lose weight

1.3 (0.7)

1.3 (0.8)

0.4 (−0.8, 1.6)

I am confident that I can…

… successfully lose weight on the assigned diet

0.9 (0.8)

1.1 (0.9)

0.2 (−1.1, 1.5)

… follow the assigned diet

−0.3 (0.7)

−0.2 (0.7)

0.0 (−1.1, 1.1)

… the degree to which the diet helped manage hunger

6.8 (0.9)

6.6 (1.0)

0.3 (−1.3, 1.8)

  1. aMean change during the 12-week intervention.
  2. bAdjusted for sex and race.
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