Fig. 3: Validation of the NGS Molecular Staging Model.
From: A molecular staging model for accurately dating the endometrial biopsy
Figure 3a. For endometrial secretory samples, POD predicted from the secretory molecular staging model was compared against the full molecular staging model. Note, POD 1 is approximately 58% of the way through the cycle. Figure 3b. Illumina HT-12 microarray data were also available from 198 endometrial samples used to generate the molecular staging model. A validation study was run comparing NGS vs Illumina data. The molecular staging model results showed a strong correlation when comparing the 2 different gene expression platforms. Figure 3c, d. Peripheral blood progesterone (n = 187) and estrogen (n = 159) data plotted against the molecular staging model cycle stage showed expected typical menstrual cycle-stage distribution. Source data are provided as a Source Data file.
