Fig. 2: Acute vasodilation of systemic vasculature.
From: In vivo noninvasive systemic myography of acute systemic vasoactivity in female pregnant mice
a Representative 3D volumes of an iliac artery in response to sildenafil over time. b Representative 3D volumes of an internal thoracic artery in response to G-1 over time. c Scatter plot of maximum increase in vessel diameter from pre-injection diameter with mean and standard deviation (n = 6 mice/group). Sildenafil and G−1 treated groups showed a significant increase compared to PBS (control) with a p-value of 0.0086 (**) assessed via one-way ANOVA followed by ad hoc t-test (two-tailed, G-1 vs. PBS p-value 0.0073(**), Sildenafil vs. PBS p-value 0.0049(**)). d Scatter plot of time to peak response of sildenafil and G-1 with mean and standard deviation (n = 6 mice/group). The color bar represents the normalized photoacoustic signal intensity. Source data are provided as a Source Data file.
