Table 2 Genotype of pups at weaning from Pacs1HET; Pacs2HET x Pacs1HET; Pacs2HET breeding

From: Neural deficits in a mouse model of PACS1 syndrome are corrected with PACS1- or HDAC6-targeting therapy

 

Pacs1 alleles

N = 121

Pacs1WT

Pacs1HET

Pacs1KO

Pacs2 alleles

Pacs2WT

E

7.56

15.13

7.56

O

13

18

7

Pacs2HET

E

15.13

30.25

15.13

O

21

38

7

Pacs2KO

E

7.56

15.13

7.56

O

5

12

0

  1. E: Expected; O: Observed. χ2 = 22.21, p = 0.0045.