Fig. 7: Diagram of HARP1 trafficking in plant.
From: Endocytosis-mediated entry of a caterpillar effector into plants is countered by Jasmonate
HARP1 is secreted from oral secretion of cotton bollworm and immigrates into plant cells. Its import is also mediated by CTL1, PATL2 and TET8 related endocytosis and vesicle trafficking. After getting into cells, HARP1 interacts with JAZs to suppress JA signaling output. On the other hand, wounding-induced JA counters HARP1 import by inhibiting endocytosis and HARP1 loading to endosomes setting up a counter-defense loop. Dash line indicates that the mechanism of JA on restriction of endocytosis requires further study.
