Fig. 5: Association of module scores in tumor-adjacent normal tissue with different variables.
From: Inflammation in the tumor-adjacent lung as a predictor of clinical outcome in lung adenocarcinoma
a Positive and negative associations of demographic, clinical, histologic, genetic and outcomes with module scores in TAN tissue. Pearson and spearman correlation tests were done for continuous and categorical variables separately. b Kaplan–Meier progression-free survival curve for patients with high (n = 62) and low (n = 61) module 20 scores in TAN tissue. 95% confidence interval was also shown in shaded blue and red. c Multi-variate modeling of time-to-progression (n = 123), log of odds ratio and data are presented as mean values with 95% confidence intervals, p-values are calculated based on Wald test for each variable. d Dot plot of c-index values between module scores and outcome (overall-survival (OS), progression-free survival (PFS) and recurrence-free survival (RFS)) per module in TCGA cohorts grouped by tissue type (non-adjusted).
