Fig. 7: Effect of Lcn2 deficiency on DAG and PA production and phospholipid-metabolizing enzymes in BAT. | Nature Communications

Fig. 7: Effect of Lcn2 deficiency on DAG and PA production and phospholipid-metabolizing enzymes in BAT.

From: Lipocalin 2 regulates mitochondrial phospholipidome remodeling, dynamics, and function in brown adipose tissue in male mice

Fig. 7

The levels of measurable PA (a–g) species and DAG species (h–j); n = 5 per group. Gene expression of DGK isoforms (k–n); n = 6 per group. Protein expression levels of phospholipid-metabolizing enzymes (o) in BAT homogenate of WT and Lcn2 KO mice treated with Saline or CL316, 243 for 14 days. Quantification of western-blotting band intensity (p–s) (n = 3 mice). Results are presented as mean ± SEM. Student’s t-test was performed to test differences between two independent groups. All tests were two-sided. The animal experiment with CL316, 243 treatment was repeated 3 times independently; n = 5–6 mice per group for each independent experiment. Source data are provided as a Source data file.

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