Fig. 5: Effect estimates of 11 CAD risk-increasing alleles on lipid species.
From: Genome-wide association analysis of plasma lipidome identifies 495 genetic associations
Variant ids are defined as rsid-risk-increasing allele. Included are species that reach the multiple testing-corrected threshold of 7.352941e-10 for at least one of the variants. Associations reaching the genome-wide-significant (P < 5e-8) or the multiple testing-corrected threshold are indicated by one or two asterisks, respectively. Colored effect estimates are shown for the associations reaching nominal significance corrected for the number of PCs explaining 90% of the variance (P < 7.352941e-4). Two-sided P-values for lipid species were calculated using a linear-mixed-model.
