Fig. 7: Interpretation study of HDRNet.

a Circos plot of the extracted binding motifs of all 172 RBP datasets. RBPs involved in the same RNA regulatory pathway are generally grouped together via hierarchical clustering. b LIN28B binding probabilities and saliency maps in HepG2 and K562 cells and the visualization of the RNA structure. c Saliency maps of RBP LIN28B under dynamic prediction tasks, where the dynamic binding motif regions are successfully identified by HDRNet and highlighted. d t-SNE clustering results of the output feature map HDRNet. It can be clearly observed that the positive and negative clusters become distinct as HDRNet processes. e The attention distribution visualization measured by the SHAP tool, where the potential binding peak is highlighted. Source data are provided as a Source Data file.