Fig. 5: VpOmpM1 and EcOmpF eyelet comparison.
From: Dual function of OmpM as outer membrane tether and nutrient uptake channel in diderm Firmicutes
a β-barrel from the C3 cryo-EM reconstruction of VpOmpM1 (top) and an EcOmpF protomer (PDB 3POQ)105 (bottom). The views are generated from a superposition. VpOmpM1 loops 3 and 7 are in green and orange, respectively; EcOmpF loop 3 is in black. Residues forming the eyelet are shown in stick representation. b Close-up view of the eyelet regions of VpOmpM1 (top) and EcOmpF (bottom). Colours as in (a). Positively and negatively charged residues lining the eyelet are annotated with a blue plus or red minus sign, respectively. c HOLE55 profiles calculated from aligned experimental structures of VpOmpM1 β-barrel and EcOmpF. The z-coordinate is perpendicular to the membrane plane and its origin is at the narrowest part of the VpOmpM1 eyelet.
