Fig. 8: Gram-scale reaction and synthetic transformations of the products. | Nature Communications

Fig. 8: Gram-scale reaction and synthetic transformations of the products.

From: Stereoselectivity control in Rh-catalyzed β-OH elimination for chiral allene formation

Fig. 8: Gram-scale reaction and synthetic transformations of the products.The alternative text for this image may have been generated using AI.

a Gram-scale reaction. b Copper-catalyzed enantioselective allenation of (R)-3ab with terminal propargylic ethers 5–8. c Synthesis of alkynyl ketone (R)-13 from (R)-3ab. d Reduction of (R)-3ad to alcohol (R)-14 with LiAlH4. e Suzuki coupling reaction of (R)-3ai to (R)-15 with 2b.

Back to article page