Fig. 4: Phenotypic differences between a selected subset of C. orthopsilosis strains under different conditions.
From: Origin of fungal hybrids with pathogenic potential from warm seawater environments
Area under the curve (AUC) inferred from measurements taken every 15 min during a period of 24 h in solid medium. a Area under the growth curve of C. orthopsilosis hybrid and parental strains (n = 8 biological replicates over 2 independent experiments) under temperatures ranging from 30 °C to 41.5 °C. Strains from the same clade or parental lineage are grouped together. Clades and parental lineages are represented in different colours. Data are presented as mean values +/− SD. b Fitness area under the curve (fAUC) of C. orthopsilosis hybrid and parental strains (n = 4 biological replicates) in the presence of anidulafungin (ANI) and fluconazole (FLZ). Green circles in the X-axis indicate marine isolates. The centre line in the boxplot indicates the median value, the boxes contain the Q1 and Q3 quartiles (IQR). The whiskers extend up to 1.5 × IQR. c Survival curves of G. mellonella injected with 106 C. orthopsilosis cells per larva (n = 15) during a period of 7 days. Difference between strains was significant with a P < 0.001 by the log rank (Mantel-Cox) test. Source data are provided as a Source Data file.
