Fig. 3: 3D variability analysis of the gp130EC complex cryo-EM map. | Nature Communications

Fig. 3: 3D variability analysis of the gp130EC complex cryo-EM map.

From: Structures of the interleukin 11 signalling complex reveal gp130 dynamics and the inhibitory mechanism of a cytokine variant

Fig. 3: 3D variability analysis of the gp130EC complex cryo-EM map.The alternative text for this image may have been generated using AI.

Refined consensus densities along, (A) variability component 1, (B) variability component 2, (C) variability component 3. Density maps are coloured according to the relative position along the variability component and arrows indicate approximate motions of the receptor domains. D Frequency distributions of the number of particles contributing to each variability component (see also Supplementary Fig. 8).

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