Fig. 8: Results of Mendelian Randomisation (MR) between sleep traits (exposure) and blood pressure (outcome) using GSMR. | Nature Communications

Fig. 8: Results of Mendelian Randomisation (MR) between sleep traits (exposure) and blood pressure (outcome) using GSMR.

From: Poor sleep and shift work associate with increased blood pressure and inflammation in UK Biobank participants

Fig. 8: Results of Mendelian Randomisation (MR) between sleep traits (exposure) and blood pressure (outcome) using GSMR.The alternative text for this image may have been generated using AI.

A summary of all MR results. MR results are only shown if they had adjusted p-value < 0.05 and the results from GSMR agreed with MR-Egger and/or weighted median MR. Data are expressed as β-estimate ±95% CI, which are presented as the centre circle and corresponding error bars, respectively. B example of the effects (β-estimate) causal association between sleep traits and blood pressure. P-values of MR are based on the 2-sided test of GSMR after adjustment of multi-testing. Adjusted pMR = 6.4e-10 for long sleep duration and diastolic blood pressure. Adjusted pMR = 9.5e-6 for long sleep duration and systolic blood pressure. Adjusted pMR = 8.7e-25 for day nap and diastolic blood pressure. Adjusted pMR = 4e-23 for day nap and systolic blood pressure. Please see also Table 2.

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