Fig. 2: Substrate scope for the formal C–C bond insertion.
From: Asymmetric formal C–C bond insertion into aldehydes via copper-catalyzed diyne cyclization
Reaction conditions: 1 (0.2 mmol), 2 (0.8 mmol), Cu(CH3CN)4PF6 (0.02 mmol), DCE (4 mL), 60 °C, 0.5–1.5 h, in vials; yields were those for the isolated products. a2b (2 mmol), 50 °C. PG = protecting group, MBS = 4-methoxybenzenesulfonyl, Bs = 4-bromobenzenesulfonyl.
