Fig. 3: SCENITH profiling and associations of metabolic profiles in mDC with OS and PFS in melanoma patients. | Nature Communications

Fig. 3: SCENITH profiling and associations of metabolic profiles in mDC with OS and PFS in melanoma patients.

From: Immuno-metabolic dendritic cell vaccine signatures associate with overall survival in vaccinated melanoma patients

Fig. 3: SCENITH profiling and associations of metabolic profiles in mDC with OS and PFS in melanoma patients.

A Box plots represent median expression values for changes in percentual SCENITH parameters in mature mDC between good (PR/SD/NED1, n = 13) and bad (PD/NED2, n = 17) outcome groups. Statistical significance was tested using Two-tailed Student’s t-test. Box plots indicate 1st, 2nd and 3rd quartile; whiskers indicate minimum and maximum. B Forest plot summarizing univariate Cox regression analyses for effects of high and low metabolic profiles (SCENITH) in mDC on overall (OS) and progression free (PFS) survival with intercept points, p-values and 95% confidence intervals indicated (n = 30). C Kaplan–Meier survival analysis of OS and PFS comparing the survival benefits of metabolic profiles (SCENITH) in mDC (n = 30). log-rank test was used to compare statistical difference between the Kaplan–Meier curves. Source data are provided as a Source Data file.

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