Fig. 7: T. brucei infection leads to upregulation of the IL-17A receptor and genes associated with lipolysis in preadipocytes. | Nature Communications

Fig. 7: T. brucei infection leads to upregulation of the IL-17A receptor and genes associated with lipolysis in preadipocytes.

From: IL-17 signalling is critical for controlling subcutaneous adipose tissue dynamics and parasite burden during chronic murine Trypanosoma brucei infection

Fig. 7: T. brucei infection leads to upregulation of the IL-17A receptor and genes associated with lipolysis in preadipocytes.The alt text for this image may have been generated using AI.

A Violin plot showing the expression level of the IL-17A receptor (Il17ra) across all cell populations in our scRNAseq dataset. B UMAP of subclustered preadipocytes. C Dot plot showing expression of genes used to identify specific populations of preadipocytes. D Frequency plot of preadipocyte populations. E Violin plot showing expression of Il17ra in specific preadipocyte populations. F Lipolysis gene module score of genes typically associated with lipolysis across all preadipocyte subsets detected in (B). Single-cell data are comprised of one technical replicate per condition, each containing pooled cells from the iWAT of five male mice. For (A, E, F), data were analysed using a one-way ANOVA.

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