Fig. 4: External validation of AnimalGAN.

a Comparison of Consistency in Toxicity Assessment Outcomes based on experiment data and AnimalGAN-generated data for all 25 measurements. The blue (left) bars represent the consistency in toxicity assessment outcomes between the experiment data from TG-GATEs and DrugMatrix. The orange (right) bars represent the consistency in toxicity assessment outcomes between the AnimalGAN-generated measurements and the experiment data tested in DrugMatrix. b Visualization of chemistry space of the 110 training compounds and the 355 external validation compounds. Each point depicts one compound. Source data are provided as a Source Data file.