Fig. 4: Native state of TMEM63C is a monomer. | Nature Communications

Fig. 4: Native state of TMEM63C is a monomer.

From: Cryo-EM structure of TMEM63C suggests it functions as a monomer

Fig. 4: Native state of TMEM63C is a monomer.

a Co-IP of TMEM63C without crosslinking. b Co-IP of TMEM63C with Glutaraldehyde (GA) crosslinking before extraction by using detergent. c Crosslink of TMEM63C-Flag in membrane with GA. d Co-IP of TMEM63B without crosslinking. All the assays are repeated at least 3 times with similar results. Proposed working model for TMEM63C (e) and TMEM63B (f). Calcium ion is indicated as blue circle.

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