Fig. 1: Schematic of the S. stipitis-S. cerevisiae consortium that converts mixed sugars to (S)-norcoclaurine. | Nature Communications

Fig. 1: Schematic of the S. stipitis-S. cerevisiae consortium that converts mixed sugars to (S)-norcoclaurine.

From: Xylose and shikimate transporters facilitates microbial consortium as a chassis for benzylisoquinoline alkaloid production

Fig. 1

PEP phosphoenolpyruvate, G6P glucose-6-phosphate, Ri5P D-ribulose-5-phosphate, X5P D-xylulose-5-phosphate, R5P ribose-5-phosphate, G3P glyceraldehyde-3-phosphate, S7P sedoheptulose-7-phosphate, F6P fructose-6-phosphate, E4P erythrose-4-phosphate, DAHP 3-deoxy-D-arabinoheptulosonate 7-phosphate, 4-HPAA 4-hydroxyphenylacetaldehyde, Xyl1 xylose reductase, Xyl2 xylose dehydrogenase, Xyl3 xylulokinase, Tkt1 transketolase, Tal1 transaldolase, SpXut1 xylose transporter free from glucose inhibition from Spathaspora passalidarum, Aro4K220L feedback-resistant DAHP synthase mutant, Aro1D900A pentafunctional arom protein mutant, AnQut quinate permeases from Aspergillus niger, Aro7G141S feedback-resistant chorismate mutase mutant, TyrHW13L,F369L yeast active tyrosine hydroxylase mutant, DODC DOPA decarboxylase, NCS norcoclaurine synthase. Dashed arrows indicate that the conversion occurs via multiple steps.

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