Fig. 2: Risk of alcohol-related cirrhosis by alcohol consumption and polygenic risk group.
From: Binge-pattern alcohol consumption and genetic risk as determinants of alcohol-related liver disease
Data are presented as hazard ratios (HRs) with respective 95% confidence intervals (CIs). All the p values were two-sided and calculated using the Wald test. HRs were derived from Cox model with following covariates: interaction of alcohol consumption and PRS groups, total weekly alcohol intake, diabetes, BMI, sex, age, ethnicity, Townsend deprivation index, physical activity, smoke, alcohol type, drinking with/without meals, genotyping array, first 10 ancestry principal components.
