Fig. 4: Related parasites share genomic regions of reduced diversity consistent with a selective sweep. | Nature Communications

Fig. 4: Related parasites share genomic regions of reduced diversity consistent with a selective sweep.

From: Malaria surveillance reveals parasite relatedness, signatures of selection, and correlates of transmission across Senegal

Fig. 4

Parasite relatedness between study sites. a Network of relatedness between all sequenced samples (clones excluded). Samples are colored by study site as indicated on the inset map. b The fraction of sample pairs that are IBD as a function of genomic position, split into samples that are (“within cluster”) or are not (“outside cluster”) part of the large network of related parasites. The four examples shown are a selective sweep around the known drug resistance locus at pfcrt (crt, green dotted line); a suspected sweep on chromosome 6 surrounding the aat1 locus (brown dotted line); a possible sweep on chromosome 12 containing the gch1 locus (pink dotted line); a possible unreported sweep on chromosome 11.

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