Fig. 3: Choroidal thickness in health and kidney disease. | Nature Communications

Fig. 3: Choroidal thickness in health and kidney disease.

From: Choroidal and retinal thinning in chronic kidney disease independently associate with eGFR decline and are modifiable with treatment

Fig. 3

A Scatter dot plots of choroidal thickness in healthy volunteers (grey, n = 86), patients with chronic kidney disease (CKD, red, n = 112) and patients with a kidney transplant (blue, n = 92) at location I (2 mm nasal to fovea), location II (subfoveal) and location III (2 mm temporal to fovea). Lines represent mean. Patients with CKD vs. health volunteers: location I *p = 0.014, location II ***p < 0.001, location III *p = 0.021; patients with a kidney transplant vs. patients with CKD, location I †p = 0.031, location II †p = 0.012. Two sided analysis by ANOVA with Tukey correction for multiple comparisons. B Scatter dot plots of subfoveal choroidal thickness (upper panel) grouped by KDIGO CKD stage as defined by estimated glomerular filtration rate (eGFR, lower panel). Red—patients with CKD stage 4/5, n = 26; Orange—patients with CKD stage 3, n = 47; Yellow—patients with CKD stage 2, n = 28; Green—patients with CKD stage 1, n = 14. Lines represent mean. Two-sided analysis by ANOVA for linear trend, p = 0.004. Source data are provided as a source data file.

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