Table 1 Study participant characteristics

From: Cell-type-specific Alzheimer’s disease polygenic risk scores are associated with distinct disease processes in Alzheimer’s disease

 

ROSMAP (n = 1457)

A4 (n = 2921)

Mean Age, years (SD)

89.7 (6.5)

71.4 (4.8)

Female (%)

973 (67)

1740 (60)

Mean Education, years (SD)

16.3 (3.6)

16.7 (2.7)a

APOE ε4 carrier (%)

376 (26)

1038 (36)

Mean Florbetapir, cortical SUVR (SD)

NA

1.10 (0.19)

Elevated Aβ (%)

1008 (69)

890 (30)b

Pathological diagnosis of AD

954 (65)

NA

Median MMSE (IQR)

24 (13)

29 (2)

All-cause dementia (%)

661 (45)

0 (0)

AD dementia (%)

539 (37)

0 (0)

  1. AD dementia, AD with dementia, APOE apolipoprotein E, IQR interquartile range, MMSE Mini-Mental State Examination, SD standard deviation, SUVR standardized uptake value ratio (whole cerebellar reference).
  2. an = 2919 with data.
  3. bn = 2920 with data.