Table 4 C-index of integrated risk model, WHO classification, mDemicco model, and G-score in discovery SYSUCC cohort and three validation cohorts
Classification | SYSUCC cohort (n = 101) | FAHSYSU cohort (n = 71) | CHCAMS cohort 1 (n = 84) | CHCAMS cohort 2 (n = 55) | ||||
|---|---|---|---|---|---|---|---|---|
C-index (95%CI) | P value | C-index (95%CI) | P value | C-index (95%CI) | P value | C-index (95%CI) | P value | |
Integrated model | 0.911 (0.846–0.976) | 1.16E−35 | 0.825 (0.727–0.923) | 9.74E−11 | 0.890 (0.786–0.994) | 1.78E−13 | 0.903 (0.803–1.002) | 3.40E−15 |
WHO classification | 0.787 (0.660–0.914) | 9.91E−06 | 0.680 (0.501–0.859) | 4.90E−02 | 0.838 (0.672–1.004) | 1.00E−04 | 0.785 (0.615–0.955) | 1.00E−03 |
mDemicco model | 0.857 (0.763–0.951) | 8.24E−14 | 0.760 (0.601–0.919) | 1.00E−03 | 0.884 (0.807–0.961) | 1.99E−22 | 0.814 (0.674–0.954) | 1.17E−05 |
G-score | 0.855 (0.749-0.961) | 5.01E−11 | 0.785 (0.637–0.933) | 2.00E−04 | 0.822 (0.655–0.989) | 1.00E−04 | 0.850 (0.747–0.953) | 2.93E−11 |
