Fig. 5: Transcriptomic analysis of liver tissue biopsies prior to machine perfusion.
From: Bile proteome reveals biliary regeneration during normothermic preservation of human donor livers
a Box plots showing individual normalized raw count transcript expression for FCGBP in high (n = 21) and low (n = 14) BDI livers and (b) correlation of transcript raw counts (x-axis) with protein intensity (-Log10; y-axis) within high and low BDI groups at 30 min and 150 min time points (n = 35). R2 and correlation p value are displayed for each comparison. Livers with high biliary viability score are represented by green, low biliary viability score with gray. The same graphs are depicted for MUC5B (c, d) and MUC1 (e, f). Data in box plots are presented as mean values showing 25th to 75th percentiles, with whiskers for minimum and maximum values. Box plot p values were calculated using two-tailed Mann–Whitney test. Correlation p values were performed using simple linear regression.
